IPOX® Health Innovation Index (IPHI)
The IPOX® Health Innovation Index (IPHI) is a diverse and dynamic portfolio consisting of leading companies in the healthcare and biotechnology sectors, focusing on recent listings (e.g. IPOs, Spin-Offs and SPACs) as well as acquirers of biotech innovation (“IPO M&As”). Using this strategy, the index captures the performance of both established and emerging players focused on innovative solutions, novel therapies, and cutting-edge medical technologies.
Key Features:
Innovation Focus: Targets companies at the forefront of healthcare advancements, from novel drug development to transformative medical technologies and services.
Diverse Exposure: Includes a mix of established large-cap pharmaceutical and healthcare leaders alongside dynamic small and mid-cap innovators.
Global Reach: Represents health innovation across key global markets, including North America, Europe, and Asia.
Rules-Based Methodology: Employs IPOX's proprietary technology to identify and weight constituents based on market cap, liquidity, and strategic M&A activity, rebalancing quarterly.
Health Innovation Themes in Focus
Global Leaders & Strategic Acquirers
The index is anchored by established global healthcare enterprises that provide stability and frequently act as strategic acquirers of innovation. These include major pharmaceutical manufacturers and diversified healthcare groups. Reflecting the index’s emphasis on recent listings and corporate actions, it also includes newly independent entities formed through 2023 spin-offs in generics and biosimilars, as well as innovation-driven large caps that actively invest in next-generation therapies.
Biotech Frontiers: Advancing Novel Therapies
A core component of the index highlights the cutting edge of biotechnology, featuring developers of therapies for unmet medical needs. Focus areas include programs for genetic diseases; cell-based treatments in oncology; antibody–oligonucleotide conjugates for rare muscle disorders; bispecific antibodies for cancer; therapies for respiratory disease; and theranostic radiopharmaceuticals. This segment captures the high-growth potential of breakthroughs in biological science.
MedTech & Health Services Innovation
Beyond therapeutics, the index captures innovation in medical technology, diagnostics, and healthcare services. This spans global med-tech manufacturers; imaging, ultrasound, monitoring, and diagnostic platforms; orthopedics, sports medicine, and advanced wound care; dialysis products and services; health savings account administration; healthcare payments automation; drug-containment and delivery systems such as prefillable syringes; and integrated medical laboratory networks. These organizations are transforming how healthcare is delivered, managed, and accessed.
The IPOX® Health Innovation Index offers investors a unique way to access the broad spectrum of healthcare innovation, from foundational large-cap players to the next generation of biotech and medtech leaders. Its dynamic approach aims to capture the companies shaping the future of global health.
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